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imChem Flash Chromatography columns

We manufacture high quality Flash Chromatography columns under strict controlled processes who guarantee their conformity relative to their specifications.
We produce our columns based under ecoFlashTM (irregular silica) and SpheriTM (spherical ultrapure silica) brand name.
We do have 2 different type of columns hardware and 1 type of Solid Injection column.

In addition, our team could support you with methods development as well as the transposition analytical to preparative methods.


1. Screw-cap column

colonne flash screw-cap 

Made from pure Polypropylene material and pure polyethylene frits. This design can withstands pressures up to 20 bar, and its 100 % leak-free performance. Columns are pre-packed with the following media : 

ecoFlashTM irregular silica

  • 500 m2/g – 60Å - 40/63 µm - loading capacity : 0.1 - 10%
  • 500 m2/g – 60Å - 50 µm - loading capacity : 0.1 - 10%

 

ecoFlash neutral alimina 50/75 µm - loading capacity : 0.1 - 4%

ecoFlash acidic alumina 50/75 µm - loading capacity : 0.1 - 4%

ecoFlash basic alumina  50/75 µm - loading capacity : 0.1 - 4% 

 

table  

 

 

 

2. Spin-Welded column

 

colonne Spin Welded

Made from pure Polypropylene material and pure polyethylene frits. This spin-welded hardware provides high performance columns from 4g to 330g that can handle pressures up to 28 bar having 100 % leak-free performance. Their Luer-Lok® fittings allows easy stacking and compatibility with any flash system.
Columns are pre-packed with the following media :

ecoFlash irregular silica Spin-Welded
500 m2/g - 60Å - 25/40 µm - loading capacity : 0.1 - 15%

C18 480 m2/g - 60Å - 40/63 µm - loading capacity : 0.1 - 2%
C18 400 m2/g - 90Å - 40/63 µm - loading capacity : 0.1 - 2%
NH2 500 m2/g - 60Å - 40/63 µm - loading capacity : 0.1 - 2%

SpheriTM Spin-Welded spherical silica
500 m2/g - 70Å - 40/75 µm - loading capacity : 0.1 - 10%
500 m2/g - 70Å - 20/45 µm - loading capacity : 0.1 - 15%
680 m2/g - 54Å - 50 µm - loading capacity : 0.1 - 30%
700 m2/g - 50Å - 25 µm - loading capacity : 0.1 - 30%
700 m2/g - 50Å - 15 µm - loading capacity : 0.1 - 30%

C18 700 m2/g - 50Å - 20/30 µm - loading capacity : 0.1 - 3%
C18 300 m2/g - 100Å - 40/75 µm - loading capacity : 0.1 - 1.5%
C18 300 m2/g - 100Å - 20/45 µm - loading capacity : 0.1 - 2%
C18 300 m2/g - 100Å - 15 µm - loading capacity : 0.1 - 2%
C18 Extreme 300 m2/g - 100Å - 20/45 µm - loading capacity : 0.1 - 2%
C18AQ 300 m2/g - 100Å - 20/45 µm - loading capacity : 0.1 - 2%
C18AQ 300 m2/g - 100Å - 15 µm - loading capacity : 0.1 - 2%
C8 300 m2/g - 100Å - 20/45 µm - loading capacity : 0.1 - 2%
C4 300 m2/g - 100Å - 20/45 µm - loading capacity : 0.1 - 2%
NH2 700 m2/g - 50Å - 20/30 µm - loading capacity : 0.1 - 2%
DIOL 700 m2/g - 50Å - 20/30 µm - loading capacity : 0.1 - 3%

  
table 

3. Solid injection column

 

Flash colonne solid injection

Made from pure Polypropylene material and pure polyethylene frits. These empty, 100% pre-packed or partially pre-packed columns are dedicated to solid or liquid injection. They can be easily manually assembled sustaining a pressure up to 7 bars. Luer-Lok® connection makes simple their stacking to the separation columns.

Solid-injection flash columns are available :

    • vide
    • 100% pre-packed – irregular silica 500 m2/g - 60Å - 40/63 µm - loading capacity : 0.1 - 10%
    • 85% préremplies - irregular silica 500 m2/g - 60Å - 40/63 µm - loading capacity : 0.1 - 2%
      • irregular silica 700 m2/g - 50Å - 25 µm - loading capacity : 0.1 - 30%
      • Acidic alumina - 50/75 µm - loading capacity : 0.1 - 4%
      • Neutral alumina - 50/75 µm - loading capacity : 0.1 - 4%
      • Alumine basique - 50/75 µm - loading capacity : 0.1 - 4%
      • irregular silica C18 480 m2/g - 60Å - 40/63 µm - loading capacity : 0.1 - 2%
      • Spherical C18 700 m2/g - 50Å - 20/30 µm - loading capacity : 0.1 - 3%
      • Spherical C18 300 m2/g - 120Å - 40/60 µm - loading capacity : 0.1 - 1.5%
      • Spherical C18 300 m2/g - 120Å - 20/45 µm - loading capacity : 0.1 - 2%
     
    table

We manufacture high quality Flash Chromatography columns under strict controlled processes who guarantee their conformity relative to their specifications.
Hereafter reports of their quality performance.

a. Repetability & Stabilty

chromatogramme superposition de 2 courbes

b. Batch to batch reproducibility

chromatogramme 2 courbes

 

3. Comparative analysis

chromatogramme 3 courbes

 

The pore volume of our silica is one of the lower, meaning lower dead volume in the column, the To is eluted earlier finally you achieve a shorter runtime of the method.*
*(at identical selectivity and for same particle size)